Cefpiramidum [INN-Latin]
Cefpiramidum [INN-Latin] - General Information
Cefpiramidum [INN-Latin] is a third-generation cephalosporin antibiotic.
Pharmacology of Cefpiramidum [INN-Latin]
Cefpiramidum [INN-Latin] is a cephalosporin active against Pseudomonas aeruginosa. It has a broad spectrum of antibacterial activity. Cefpiramidum [INN-Latin] works by inhibiting bacterial cell wall biosynthesis. The plasma half-lives of cefpiramide in rabbits, dogs, and rhesus monkeys were much longer than those of cefoperazone and cefazolin.
Additional information about Cefpiramidum [INN-Latin]
Cefpiramidum [INN-Latin] Indication: For treatment of severe infections caused by susceptible bacteria.
Mechanism Of Action: The bactericidal activity of cefpiramide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cefpiramide
Synonyms: Not Available
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Cefpiramide: Cefpiramide Sodium; Cefpiramide [USAN-INN]; Cefpiramido [INN-Spanish]; Cefpiramidum [INN-Latin];
Absorption: Rapidly absorbed following intramuscular injection.
Toxicity (Overdose): Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: 4.44 hours
Dosage Forms of Cefpiramidum [INN-Latin]: Not Available
Chemical IUPAC Name: (6R)-7-[[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C25H24N8O7S2
Cefpiramide on Wikipedia: https://en.wikipedia.org/wiki/Cefpiramide
Organisms Affected: Enteric bacteria and other eubacteria